For folks who don't have time to read comments, I thought I'd repost the great comment to the post below from Catherine Ryan Hyde, author of Pay it Forward and a whole lot of other brilliant novels:
"Trends change so regularly that you will most often miss them if you try to write to fit them. And if you fake an interest in, say, romance, the lack of genuine interest usually tanks the work. I always thought the best plan was to write what you truly love. The love comes through and the work rises like cream to the surface, even in a tough market. Who knows, maybe next year I'll sell When I Found You in the US. I'm not betting the house on it, but stranger things have happened. Especially in publishing."